ea0089b1 | Basic Science | NANETS2022
Rajhans Shreya
, Mondell Ethan
, Madigan James
, Truongvo Nhi
, Wang Li
, Kelly Michael
, Sadowski Samira M.
, Efsun Arda H.
Background: Pancreatic neuroendocrine tumors (PNETs) are a rare, understudied form of cancer with few curative options, and their occurrence is rising. With approximately 4,000 new cases diagnosed per year in the US, and a 5-year relative survival rate of 54%, itÂ’s imperative to understand the molecular mechanisms governing PNET carcinogenesis. To date, most studies used whole-tumor sequencing to characterize PNETs, which hampers the discovery of their microenvironment, c...